Bin Yu, Professor in the Departments of Statistics and Electrical Engineering and Computer Sciences at the University of California, Berkeley, along with a team of scientists helped develop computational techniques to identify and understand the hidden ways epistasis influences inherited diseases. In collaboration with Euan Ashley, Professor of Genetics and of Biomedical Data Science at Stanford along with a team of scientists, Bin was a co-corresponding author in a recent published study in Nature Cardiovascular Research that established epistatis as a key driver of cardiac hypertrophy, a condition in which the heart thickens, resulting in a restriction of the heart's ability to pump blood. Their work identifying gene-pair interactions could improve the diagnosis and treatment of heart disease as well as open a door to deeper understanding of a wide variety of other complex genetic disorders.
January 28, 2026