Research Fields: Biophysics, Epigenomics, Evolutionary Biology and Phylogenetics, Gene Expression and Regulation, Genomics and Genetics, Machine Learning and Algorithms, Network and Systems Biology, RNA Biology
A major focus of his lab is to develop novel molecular tools that make it possible to dissect and rewire these gene circuits at the DNA and RNA levels and to uncover the biological mechanisms behind neurodegenerative and immune-related disorders, and exploit this new knowledge to develop therapeutic strategies that endow cells with genetic upgrades to combat diseases. Other interests include developing engineered vehicles for therapeutic macromolecule delivery, and leveraging library screens and brain organoids to interrogate human neuroscience at scale.
