CCB Seminar: Evolutionary forces shape the genetic architecture of complex traits

125 Li Ka Shing Center

Dr. Ryan Hernandez, UCSF Talk will also be broadcast via Zoom: https://berkeley.zoom.us/j/99535189861 Abstract: Human evolutionary history has included waves of migration across the world, substantial population bottlenecks, and super exponential growth. Humans have also experienced rapid adaptation to novel environments and pathogens, as well as the relentless force of purifying selection purging deleterious mutations. While […]

CCB Seminar: The effects of cross-trait assortative mating on genetic correlation estimators

125 Li Ka Shing Center

Dr. Noah Zaitlen, Assistant Professor, UCLA Abstract: Positive genetic correlation estimates are commonly interpreted as evidencethat two traits share overlapping biological features. With the increasing avail-ability of large consortium and biobank datasets, considerable research activityhas focused on cataloging the genetic correlation structure of complex humantraits in order to better understand shared etiology and transdiagnostic riskfactors. […]