CCB Seminar: Toward understanding RNA binding and regulation

Zoom Seminar

Dr. Daniel Dominguez, Assistant Professor, Department of Pharmacology, UNC Chapel Hill Abstract: RNA binding proteins (RBPs) modulate all stages of an RNA’s life cycle, including transcription, splicing, localization, translation, and degradation. Accordingly, RBPs control important biological events (e.g. development), and altered RBP function is a prevalent cause of disease. Using large-scale biochemical assays, we explored […]

CCB Seminar: Adventures in single-cell analysis

Zoom Seminar

Dr. William Noble, Professor, Department of Genome Sciences, University of Washington Abstract: In this talk, I will describe several recent efforts in my lab to help facilitate the analysis of large, single-cell genomics datasets. First is an unsupervised learning method that aims to find shared manifold structure in so-called "multi-omics" datasets, where different aliquots of […]